The He laboratory is interested in understanding the molecular basis for environmental carcinogenesis and therapeutic resistance, and focuses on the role of epitranscriptomics, epigenetics, and autophagy in regulating genomic integrity and cellular homeostasis and to investigate their impact on cancer development and therapeutic resistance.
Transcriptional and post-translational mechanisms regulating DNA damage response
Autophagy in stress response and environmental tumorigenesis
RNA modifications and DNA modifications in stress response, environmental carcinogenesis, and cancer therapeutic response
